The league's streaming service for out-of-market games registered 11.5 billion minutes watched.
Additionally, the ManningCast featuring Peyton and Eli Manning saw its biggest audience this season.
Alabama-Arkansas drew an average of 5.828 million viewers, making it the most-watched Alabama-Arkansas game in 12 years.
Saturday's broadcast of Michigan-Iowa drew 4,198,000 viewers on FOX.
That number buoys the network to an average of 18.559 million viewers over the first four games of the season.
FOX reeled in 2,657,000 viewers for its two game slate (Rays-Astros or Mets-Braves).
That figure represents growth from last week's Steeler-Browns game which averaged 11.03 million viewers.
Last weekend's show from Appalachian State University averaged 2.2 million viewers. ESPN reported that figured was up 15% compared to Week 3 in 2021.
According to the network, the nearly 21 million average was better than the Week 1 figure across the same networks.
The network's Big Noon Saturday game is averaging 7,160,000 viewers which is up 18% from the first three weeks of 2021 (6,053,000 viewers).